I am currently working on APP organization at synaptic level and it's role in Alzheimer's disease (AD)
Project: My research is focused on studying a protein family called Mint family of protein, which is a scaffolding protein for Amyloid precursor protein. Here we study the influence of Mint family proteins on the localization, trafficking and processing of APP.
Pallavi Rao Netrakanti
Project: Nanoscale organization of pre-synaptic calcium sensors regulating synchronous and asynchronous neurotransmitter release.
I completed my MSc Biotechnology from IBB, SP Pune University. Enrolled as a Ph.D. student since 2015, I have been working on various proteins and their interactions and how they influence endocytosis. My work is focussed on clathrin mediated endocytosis and how endocytic complexes can affect the proteins on the synaptic plasma membrane.
Understanding these processes may improve our knowledge of various pathologies which are seen in Alzheimer's Disease. I am passionate about research and will continue to work in academic field. In free time I read manga or watch anime or sketch something I found was interesting.
I am a third year PhD student. I did my graduation in B.Sc. Forestry and currently pursuing a direct PhD in Molecular Neuroscience. My field of interest is Synaptic Transmission and Plasticity in neurons. Synapse associated protein-97 (Sap-97), a scaffolding molecule at the cellular junctions is the protein which I am working and trying to understand, “The role of Sap-97 in Nanoscale organization and regulation of synaptic transmission”.
Our Lab utilizes state of the art Microscopic imaging techniques such as FRAP, SRRF etc. and for obtaining Nanoscale Resolution we use STED, PALM and STORM. We also do Molecular biology, Biochemistry and Cell culture works.
I have a Master of Science degree in Stem cell biology from University of Minnesota along with 2 years of working in the field of neuroscience. My projects included working on the differentiation of human induced Pluripotent Stem (iPS) cells into oligodendrocyte progenitor cells for use in cell therapy models for spinal cord injury. I also worked on developing and characterising cerebral organoids from human iPS cells with the help of a 3D scaffold. Currently in the lab, my main interest lies in studying the nano-scale organization of AMPA receptors in primary hippocampal cultures and the effect of homeostatic plasticity on their organization. In future, I plan to use super-resolution microscopy techniques like STED and STORM to better understand the effect of homeostatic plasticity on AMPA receptor organization.
I received my bachelor's degree in IT and Mathematical Innovation from Cluster Innovation Center, University of Delhi. In the lab I am involved in studying the effects of homeostatic scaling on the nano organisation of AMPA receptors and improvising the tools that involve the analysis of organisation and structure of these nanodomains. My research interests include the physical and chemical composition of memory models over time.
Litralson E R
For my bachelors, I worked on mitochondrial distribution in Neuro2A cell lines. I'm currently working on my masters thesis and looking into other organelle distributions with the help of SRRF analysis.