Naren Ramanan

Associate Professor

Phone : +91 80 2293 3532
E-Mail : naren[at]iisc.ac.in
web : www.cns.iisc.ac.in/naren/

Research Areas

Developmental neurobiology

Research Details

Developmental neurobiology
  1. What are the molecular mechanisms regulating axonal growth during development and how these mechanisms can be activated to promote axonal regeneration after injury.
  2. What are the mechanisms regulating neural stem cells to astroglial differentiation in the brain? How do these mechanisms go awry in gliomas, the major tumours in the brain?

His lab uses a combination of mouse genetics, molecular, biochemical and cell biological approaches to understand various aspects of central nervous system development.


Mani S*, Radhakrishnan S, Cheramangalam RN, Shalini H, Rajendran S and Ramanan N*, (2020), Shh mediated increase in β-catenin levels maintains cerebellar granule neuron progenitors in proliferation, Cerebellum , 19:, 645–664

Mandal P, Belapurkar V, Nair D and Ramanan N, (2020), Vinculin mediated axon growth requires interaction with actin but not talin, bioRxiv

Chatterjee A, Chinappa K, Ramanan N, Mani S, (2018), Centrosome inheritance does not regulate cell fate in granule neuron progenitors of the developing cerebellum, Cerebellum, 17:, 685-691

Donlea JN, Ramanan N, Silverman N and Shaw PJ , (2014), Genetic rescue of functional senescence in synaptic and behavioral plasticity, Sleep, 37: 1427-1437

Li CL, Sathyamurthy A, Oldenborg A, Tank D and Ramanan N , (2014), Glycogen synthase kinase-dependent axon growth is mediated by SRF-dependent transcription in CNS neurons, J Neurosci, 34 (11): 4027-4042

Lu PPY and Ramanan N, (2012), A critical cell-intrinsic role for serum response factor in glial specification in the CNS, J. Neurosci. 32: 8012-23, PMID: 22674276

Lin C, Hinde A, Burns CJ, Yin Y, Koppel A, Ma L, Blumenberg M, Khnykin D, Jahnsen FL, Crosby SD, Ramanan N, and Efimova T, (2012), Serum Response Factor controls transcriptional network regulating epidermal function and hair follicle morphogenesis, J. Invest. Dermatol. 133: 608-617, PMID: 23151848

Lu PPY and Ramanan N, (2011), Serum Response Factor is required for cortical axon growth but is dispensable for neurogenesis and neocortical lamination, J. Neurosci. 31:16651-64, PMID: 22090492

Johnson AW, Rombag HS, Smith DR and Ramanan N, (2011), Effects of serum response factor (SRF) deletion on conditioned reinforcement, Behav Brain Res. 220:312-8, PMID: 21329726